A 64 years male was admitted in our hospital on 20th August 2019, with complaints of high grade fever, breathlessness and drowsiness. He is known case of Diabetes Mellitus, Ischemic Heart Disease, Chronic obstructive pulmonary disease, Parkinson’s disease, Cerebral Vascular disease and congestive cardiac failure on regular treatment. He was diagnosed with sepsis meningoencephalitis and treated with appropriate IV antiviral & IV antibiotics. After a few days of treatment he started responding minimally to commands but remained aphasic and generally unresponsive. Due to our intensive treatment, good nursing care, regular physiotherapy and speech therapy he has now started communicating, talking, taking meals orally, in our subsidized treatment ward..